Metabolism: What Causes the Gut's Circadian Instincts?

نویسندگان

  • Jeffrey M. Gimble
  • Z. Elizabeth Floyd
چکیده

What mechanisms control circadian rhythms in the gastrointestinal tract and how does this impact nutrient metabolism? The deadenylase and leucine zipper protein Nocturnin is now shown to play a central role.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Social Implication of Internal Instincts and Hidden Motives in O’Neill’s Mourning Becomes Electra

American playwright, Eugene Gladstone O’Neill (1888-1953) is presenter of truth without comprising his beliefs. His works are dramatized by passion elements such as memories, dreams, and by awareness of forces. During mid-1920s he became interested in dramatizing complicated pattern of his family’s life. Mourning Becomes Electra, which opened on Oct. 26, 1931, and had fourteen acts, was O'Neill...

متن کامل

Effect of Eight Weeks of Endurance Training in Light and Dark Phases of Circadian Rhythm on the Oxidative Stress Index in Pancreas of Diabetic Mice

Introduction: Chronic hyperglycemia is associated with an increase in cellular damage due to oxidative stress in pancreatic tissue. The effect of exercise in different phases of the circadian cycle on protecting pancreatic tissue from oxidative stress in diabetic patients is unknown. The aim of this study was to investigate the effect of eight weeks of endurance training in light and dark phase...

متن کامل

Rhythms in Energy Storage Control the Ability of the Cyanobacterial Circadian Clock to Reset

Circadian clocks are oscillatory systems that schedule daily rhythms of organismal behavior. The ability of the clock to reset its phase in response to external signals is critical for proper synchronization with the environment. In the model clock from cyanobacteria, the KaiABC proteins that comprise the core oscillator are directly sensitive to metabolites. Reduced ATP/ADP ratio and oxidized ...

متن کامل

A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism.

Disruption of the circadian clock exacerbates metabolic diseases, including obesity and diabetes. We show that histone deacetylase 3 (HDAC3) recruitment to the genome displays a circadian rhythm in mouse liver. Histone acetylation is inversely related to HDAC3 binding, and this rhythm is lost when HDAC3 is absent. Although amounts of HDAC3 are constant, its genomic recruitment in liver correspo...

متن کامل

Why we need to read and understand literature: literariness and Hans Rosling’s Factfulness (2018)

My article addresses the qualities of “good” literature and how an understanding of the nature of literary devices, so-called “literariness”, can enhance the reading experience. Focusing on Hans Rosling’s Factfulness (2018), I discuss some of the most important features of good writing. Six literary devices have been selected for special attention: point of view, tone, amplification, anecdotes,...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Current Biology

دوره 21  شماره 

صفحات  -

تاریخ انتشار 2011